Epidemiologic and Clinical Features of Mpox in Adults Aged >50 Years — United States, May 2022–May 2023

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Childhood smallpox vaccination confers some cross-protection against mpox. Although persons aged >50 years likely received childhood smallpox vaccination, they might have more comorbidities and a higher risk for severe mpox compared with those aged ≤50 years. Information about waning cross-protective immunity and how this might affect risk for severe mpox is limited. What is added by this report? Among 29,984 adults with mpox, those aged >50 years had higher prevalences of immunocompromising conditions and HIV and lower prevalence of symptoms than did those aged ≤50 years. Among […]

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