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Working underground in a Biosafety Level 3 insectary in Tres Cantos, Madrid, researchers at the pharmaceutical giant GSK were frustrated.

The mosquitoes they were using to study experimental medicines for malaria had developed a pesky problem: They were becoming resistant to the parasite, plasmodium, that causes the ancient disease.“We needed to get this testing up and running as soon as possible,” said Dr. Janneth Rodrigues, GSK’s scientific leader of global health medicines research and development. “So we tried to find out the reasons for this loss of susceptibility.”It turned out that the mosquitoes harbored a bacteria that secreted […]

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By Donato